Plasminogen Activators in Ischemic Stroke: Introduction
نویسندگان
چکیده
منابع مشابه
Approaches to Thrombolysis Plasminogen Activators in Ischemic Stroke Introduction
A number of plasminogen activators (PAs), enzymes capable of converting the zymogen plasminogen to the active agent plasmin, have been studied as potential therapeutic agents in the settings of ischemic stroke, intracerebral parenchymal hemorrhage, and large vessel thrombosis. Several have found purpose in the acute management of focal cerebral ischemia under strictly limited conditions. All de...
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Background: Thrombolytic therapy is the recommended treatment of acute ischemic stroke. It is crucial to evaluate the treatment results with recombinant Tissue Plasminogen Activator (r-TPA) in patients with acute stroke. Objectives: This study aimed to evaluate treatment outcomes with r-TPA in patients with acute stroke in a referral stroke center in Iran. Materials & Methods: In this retrosp...
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T he only treatment shown to improve outcome in acute ischemic stroke is tissue-type plasminogen activa-tor administered within 3 hours (and perhaps longer) after stroke onset. Definitive data to support a role for acute endovascular stroke therapy, however, are lacking. Despite this lack of data, endovascular therapy is being used much more widely and has become the standard of care in many re...
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ژورنال
عنوان ژورنال: Stroke
سال: 2010
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.110.595769